Keterangan :

How does Honvan work?
Fosfestrol tetrasodium is an inactive synthetic oestrogen ( female sex hormone) which is converted in the body to an active oestrogen, diethylstilbestrol. It used in the treatment of prostate cancer. Prostate cancer grows more rapidly under the influence of the male sex hormones ( androgens) . Oestrogen can lower blood levels of androgens, counteract their effects at the tumour site and cause the tumour to reduce in size. Fosfestrol relieves the urinary symptoms, such as poor flow, by shrinking the tumour.

What is Honvan used for?

Prostate cancer

Use with caution in :

Diabetes
Disease involving the heart and blood vessels ( cardiovascular disease)
Disease of the blood vessels in and around the brain ( cerebrovascular disease)
Disorders that increase the risk of blood clots in the blood vessels ( thromboembolic disorders)
High blood pressure ( hypertension)
Liver disease
People over the age of 75 years

Not to be used in :

Known sensitivity or allergy to any ingredient
This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy. If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.

Pregnancy and Breastfeeding :
Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.

This medicine should not be used during pregnancy as it may be harmful to the unborn baby. Seek medical advice from your doctor.
There is no information available regarding the safety of this medicine during breastfeeding. Seek medical advice from your doctor.

Side Effects :
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.

Abdominal cramps
Impotence
Skin rashes
Visual disturbances
Yellowing of the skin and eyes ( jaundice)
Abnormal enlargement of breasts in men ( gynaecomastia)
Fever ( pyrexia)
Retention of water in the body tissues ( fluid retention)
High blood calcium level ( hypercalcaemia)
Dizziness
Bone pain
Loss of appetite
Blood clots in the blood vessels ( thrombosis) that may detach and travel in the circulation to another area of the body ( thromboembolism)
Nausea and vomiting

The side effects listed above may not include all of the side effects reported by the drug' s manufacturer.

For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

How can this medicine affect other medicines?

This medicine is not known to interact with any other medicines, food or alcohol.

Indications :
Treatment of prostatic carcinoma. May be used as an adjuvant to surgery, in inoperable cases and surgery, in inoperable cases and for the reduction of pain due to metastases.

Specifications

Brand Name Honvan Tablets
Manufactured By Baxter Oncology
Contents Fosfestrol tetrasodium 120mg