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    ITRACONAZOLE Impurities & Metabolites

    ITRACONAZOLE Impurities & Metabolites

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    ICZ01: Itraconazole

    4-[ 4-[ 4-[ 4-[ [ cis-2-( 2, 4-Dichlorophenyl) -2-( 1H-1, 2, 4-triazol-1- ylmethyl) -1, 3-dioxolan-4-yl] methoxy] phenyl] piperazin-1-yl] phenyl] -2-[ ( 1RS) -1 -methylpropyl] -2, 4-dihydro-3H-1, 2, 4-triazol-3-one
    [ CAS # 84625-61-6]

    ICZ02: Itraconazole EP Impurity A

    4-[ 4-[ 4-( 4-Methoxyphenyl) piperazin-1-yl] phenyl] -2-[ ( 1RS) -1-methylpropyl] - 2, 4-dihydro-3H-1, 2, 4-triazol-3-one
    [ CAS # 252964-68-4]

    ICZ03: Itraconazole EP Impurity B

    4-[ 4-[ 4-[ 4-[ [ cis-2-( 2, 4-Dichlorophenyl) -2-( 4H-1, 2, 4-triazol-4-ylmethyl) -1 , 3-dioxolan-4-yl] methoxy] phenyl] piperazin-1-yl] phenyl] -2-[ ( 1RS) -1-methylprop yl] -2, 4-dihydro-3H-1, 2, 4-triazol-3-one
    [ CAS # 854372-77-3]

    ICZ04: Itraconazole EP Impurity C

    4-[ 4-[ 4-[ 4-[ [ cis-2-( 2, 4-Dichlorophenyl) -2-( 1H-1, 2, 4-triazol-1-ylmethyl) -1 , 3-dioxolan-4-yl] methoxyphenyl] piperazin-1-yl] phenyl] -2-propyl-2, 4-dihydro-3 H-1, 2, 4-triazol-3-one
    [ CAS # 74855-91-7]

    ICZ05: Itraconazole EP Impurity D

    4-[ 4-[ 4-[ 4-[ [ cis-2-( 2, 4-Dichlorophenyl) -2-( 1H-1, 2, 4-triazol-1-ylmethyl) -1 , 3-dioxolan-4-yl] methoxy] phenyl] piperazin-1-yl] phenyl] -2-( 1-methylethyl) -2, 4 -dihydro-3H-1, 2, 4-triazol-3-one
    [ CAS # 89848-49-7]

    ICZ06: Itraconazole EP Impurity E

    4-[ 4-[ 4-[ 4-[ [ trans-2-( 2, 4-Dichlorophenyl) -2-( 1H-1, 2, 4-triazol-1-ylmethyl) -1, 3-dioxolan-4-yl] methoxy] phenyl] piperazin-1-yl] phenyl] -2-[ ( 1RS) -1-methylpr opyl] -2, 4-dihydro-3H-1, 2, 4-triazol-3-one
    [ CAS # 84604-65-9]

    ICZ07: Itraconazole EP Impurity F

    2-Butyl-4-[ 4-[ 4-[ 4-[ [ cis-2-( 2, 4-dichlorophenyl) -2-( 1H-1, 2, 4-triazol-1-ylm ethyl) -1, 3-dioxolan-4-yl] methoxy] phenyl] piperazin-1-yl] phenyl] -2, 4-dihydro-3 H-1, 2, 4-triazol-3-one
    [ CAS # 89848-51-1]

    ICZ08: Itraconazole EP Impurity G

    4-[ 4-[ 4-[ 4-[ [ cis-2-( 2, 4-Dichlorophenyl) -2-( 1H-1, 2, 4-triazol-1-ylmethyl) -1 , 3-dioxolan-4-yl] methoxy] phenyl] piperazin-1-yl] phenyl] -2-[ [ cis-2-( 2, 4-dichlo rophenyl) -2-( 1H-1, 2, 4-triazol-1-ylmethyl) -1, 3-dioxolan-4-yl] methyl] -2, 4-dihy dro-3H-1, 2, 4-triazol-3-one



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